Answer: (b).
Statement 1 is true. Actisite is a 23cm monofilament of ethylene vinyl acetate impregnated with 12.7mg (0.5mg/cm) of tetracycline. When placed in the pocket for ten days it reaches 100 times the peak levels achieved with systemic oral administration. Indications are sites that fail to respond to conventional therapy.
Statement 2 is true. It is a prescription capsule used in conjunction with scaling and root planning. It is a unique form of doxycycline (20 mg caps). It uses the collagenalytic (collagenase inhibitors) properties of tetracycline while limiting bacterial resistance.
Statement 3 is not accurate. The Periochip is a 4X5 mm firm gelatin strip impregnated with chlorhexadine. It is inserted into pockets 5mm or greater. It is used as a supplement to scaling and root planning.
Statement 4 is not accurate. Arestin contains minocycline HCL (1mg). Microspheres containing the drug are inserted into the pocket. It is used as an adjunct to scaling and root planning. The microspheres are a polymer material that is bioadhesive, bioresorbable. Once inserted it adheres to the periodontal pocket. The drug is slowly released by diffusion form the spheres to the pocket. Arestin maintains therapeutic drug levels for at least 14 days.
Statement 5 is correct. It is a gel that solidifies in the pocket and releases tetracycline over a seven day period
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