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Tuesday, November 13, 2007

Genral Medicine MCQ Answer 2

Tuesday, November 13, 2007

Answer is E

The risk for developing diabetes increases in certain cases such as the following.

  • Genetics - People with a close relative with type 2 diabetes are at higher risk.

  • Ethnic background - For example, the actual prevalence of diabetes in the Caucasian population of the US is about 7.2% while in the African American population, it increases to about 11%. In a well known group of Native Americans, the Pima Indians, the prevalence increases to almost 35%.

  • Birth weight - There is a relationship between birth weight and developing diabetes, and it's the opposite of what you'd intuitively think. The lower the birth weight the higher the risk of type 2 diabetes.

  • Metabolic syndrome - People who have the metabolic syndrome are at especially high risk for developing diabetes.

  • Obesity - Obesity is probably the most impressive risk factor. This is in part due to the fact that obesity increases the body's resistance to insulin. Studies have shown that reversal of obesity through weight reduction improves insulin sensitivity and regulation of blood sugar. However, the distribution of fat is important. The classic "pear" shape person (smaller waist than hips) has a lower risk of developing diabetes than the "apple" shape person (larger around the waist). The exact reason for this difference is unknown, but it is thought to have something to do with the metabolic activity of the fat tissue in different areas of the body.


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