Which of the following require antibiotic prophylaxis?
1. Organic heart murmur
2. Cardiac pacemakers
3. Isolated secundum atrial septal detect
4. Previous history of endocarditis
5. Most artificial joint patients
a. 1,4
b. 2,5
c. 1,3,5
d. 1,2,3,4
e. all of the above

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