Which of the following are true regarding host defense response to the threat of microbial invasion from the root canal?
The plasma cells are the front line fighting force against bacteria.
The T-lymphocytes, B-lymphocytes and natural killer cells are primary cells of importance in chronic inflammation and immunity
Plasma cells are the only cells that can manufacture and secrete antibodies
PMNs have a life of 8-10 days and die in great numbers at acute inflammatory sites
The accumulation and local death of neutrophils is a major cause for tissue breakdown in chronic phases of apical periodontitis
1 only is correct
2 only is correct
3 only is correct
2, 4, and 5 are correct
All of the above are correct

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