Oral Pathology MCQ Answer 2

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Answer is D

Clinically the lesions appear as a painless nodular or papular
elevation with a small central crater and smooth or pappillomatous
surface.It is sessile with whitish or normal color and a diameter
ranging from a few millimeter to 1 cm

Histopathology

• Circumscribed
• Cup-shaped
• Invaginating
• Extends into underlying dermis
  

  Fig. 1: Warty dyskeratoma. A cup-shaped invagination is filled with a keratinous plug, which in turn overlies an area of suprabasal clefting.
  

• Central depression:
  • filled with plug of keratinous material containing some grains:
    • keratin plugs sometimes dislodged, particularly in oral lesions
• Epidermal component:
  • suprabasilar clefting:
    • numerous acantholytic and dyskeratotic cells within lacuna
• Dermal papillae (villi):
  -covered by layer of basal cells
  -protrude into lacuna
  
  • contain:
  dilated vessels
  occasional melanophages
  few inflammatory cells also present in underlying dermis
• Pilosebaceous follicles may open into lesion
• Corps ronds and grains:
  • better developed in skin lesions than in those in mouth